The Thymus and the Bursa of Fabricius in Chickens
نویسندگان
چکیده
The effect of cyclephosphamide (Cy) on the thymus and the bursa of Fabricius in chickens, aged one day to 7 weeks, was examined morphologically, Chiekens, which were daily injected i.m. with 6mg Cy 1, 2, or 3 times from the hatching day, were compared with saline coutrel chickens, The relative weights of both the thymus and the bursa decreased abruptly just after the injection of Cy. The weight of the thymus had an involutional bottem at the age ef 4.v5 days, and thereafter recovered to the normal leve] at age 3 weeks, while that of the bursa never returned to the control level unt{1 age 7 weeks. The hlstological changes in the thymus appeared to be greater in the cortex than in the medulla. A degeneration of lymphocytes, an increase of macrophages, hypertrophy of the reticular cells, and a disappearance of mitotic cells were observed in the cortex during early involutien. Recovery began as soon as the large lymphocytes appeared in the cortex, and the histological structures of the
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Histologic Lesions of Thymus and Bursa of Fabricius in Commercial Broiler Chickens Inoculated with H9N2 Avian Influenza Virus
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